Call us on 0800 019 0053 We are open today between 9am and 8pm
A cruise from San Diego is the perfect way to see the delights of the Mexican Riviera to the south or further up the Californian coast along the western seaboard all the way north to Vancouver, even as a one-way trip. Alternatively, there are also many itineraries departing for round-trip sailings to Hawaii. Typically with a duration of 7 to 10 days, whether you're a couple, family or solo traveller, and with plenty of flights options out of the UK to San Diego International Airport, you'll easily find the best cruise departing San Diego for you for 2027, 2028 and 2029 with Scotland's Cruise Centre. Call one of our friendly Cruise Experts and book your dream San Diego cruise adventure today!
Koningsdam 28 November 2026 10 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Mazatlan - Puerto Vallarta - San Diego
Cruise Only from
Includes extra savings of up to £111pp
Disney Wonder 29 November 2026 5 nights
Itinerary: San Diego - Cabo San Lucas - Ensenada - San Diego
Cruise Only from
Zaandam 07 December 2026 12 nights
Itinerary: San Diego - Cabo San Lucas - Guayamas - Topolobampo - La Paz - Mazatlan - Puerto Vallarta - Ensenada - San Diego
Cruise Only from
Includes extra savings of up to £140pp
Koningsdam 08 December 2026 11 nights
Itinerary: San Diego - Manzanillo - Puerto Vallarta - Mazatlan - La Paz - Cabo San Lucas - San Diego
Cruise Only from
Includes extra savings of up to £117pp
Serenade of the Seas 13 December 2026 7 nights
Itinerary: San Diego - Catalina Island - Ensenada - Cabo San Lucas - San Diego
Cruise Only from
Koningsdam 19 December 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Mazatlan - San Diego
Cruise Only from
Includes extra savings of up to £92pp
Koningsdam 19 December 2026 14 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Mazatlan - San Diego - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego
Cruise Only from
Includes extra savings of up to £138pp
Zaandam 19 December 2026 15 nights
Itinerary: San Diego - Cabo San Lucas - Puerto Vallarta - Santa Cruz - Puerto Quetzal - Puntarenas - Cartagena - Fort Lauderdale
Call us now on 0800 019 0053
Serenade of the Seas 20 December 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - La Paz - Mazatlan - San Diego
Cruise Only from
Norwegian Star 20 December 2026 6 nights
Itinerary: San Diego - Puerto Vallarta - Cabo San Lucas - San Diego
Cruise Only from
Includes extra savings of up to £46pp
Luxury
Crystal Serenity 21 December 2026 9 nights
Itinerary: San Diego - Topolobampo - Loreto - La Paz - San Diego
Cruise Only from
Luxury
Crystal Serenity 21 December 2026 18 nights
Itinerary: San Diego - Topolobampo - Loreto - La Paz - San Diego - Manzanillo - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego
Cruise Only from
Disney Wonder 22 December 2026 7 nights
Itinerary: San Diego - Ensenada - Cabo San Lucas - Puerto Vallarta - San Diego
Cruise Only from
Norwegian Star 26 December 2026 7 nights
Itinerary: San Diego - Cabo San Lucas - Mazatlan - Puerto Vallarta - San Diego
Cruise Only from
Includes extra savings of up to £66pp
Koningsdam 26 December 2026 7 nights
Itinerary: San Diego - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego
Cruise Only from
Includes extra savings of up to £76pp
Koningsdam 26 December 2026 14 nights
Itinerary: San Diego - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego - Cabo San Lucas - La Paz - Guayamas - San Diego
Cruise Only from
Includes extra savings of up to £129pp
Serenade of the Seas 27 December 2026 7 nights
Itinerary: San Diego - Mazatlan - La Paz - Cabo San Lucas - San Diego
Cruise Only from
Disney Wonder 29 December 2026 5 nights
Itinerary: San Diego - Catalina Island - Ensenada - San Diego
Cruise Only from
Luxury
Crystal Serenity 30 December 2026 9 nights
Itinerary: San Diego - Manzanillo - Puerto Vallarta - Mazatlan - Cabo San Lucas - San Diego
Cruise Only from
Norwegian Star 02 January 2027 7 nights
Itinerary: San Diego - Cabo San Lucas - Puerto Vallarta - Mazatlan - San Diego
Cruise Only from
Includes extra savings of up to £35pp
Very thorough and informative
Trusted Customer / October 2026
You always provide excellent service and are quick to get back with prices
Trusted Customer / October 2026
Knowledgeable staff member who was able to answer all my questions. Staff member communicated quickly.
Mrs Goodwin / October 2026
At Scotland's Cruise Centre there are a number of ways you can contact us meaning that all you have to do is choose the option which is most convenient to you.
Request a Callback
Get A Quote
At Scotland's Cruise Centre there are a number of ways you can contact us meaning that all you have to do is choose the option which is most convenient to you.
Get A Quote
Request A Callback
Sign up today for exclusive savings